Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

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Tuesday, November 3, 2009

Drunken fruit flies help scientists find potential drug target for alcoholism


A group of drunken fruit flies have helped researchers from North Carolina State and Boston universities identify entire networks of genes—also present in humans—that play a key role in alcohol drinking behavior. This discovery, published in the October 2009 print issue of the journal GENETICS, provides a crucial explanation of why some people seem to tolerate alcohol better than others, as well as a potential target for drugs aimed at preventing or eliminating alcoholism. In addition, this discovery sheds new light on many of the negative side effects of drinking, such as liver damage. . . . . . .

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