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Tuesday, June 16, 2009

High Level of α-Synuclein mRNA in Peripheral Lymphocytes of Patients with Alcohol Dependence Syndrome
Bulletin of Experimental Biology and Medicine Volume 146, Number 5 / November, 2008 pp.609-611
The content of mRNA for α-synuclein (a key protein of the dopaminergic system) was elevated in the peripheral lymphocytes of patients with alcohol dependence syndrome. Increased level of α-synuclein mRNA was not associated with changes in the expression of NR4A2 gene encoding Nurrl, one of the main transcription factors of dopaminergic neurons.
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