Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

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Saturday, May 23, 2009

Complete Suppression of Craving in Alcohol-Dependent Individuals: Is It Possible?
CNS Drugs. 23(5):361-367, May 19, 2009.

A recent preliminary, single-case report suggested that baclofen not only reduces but may completely suppress craving in alcohol-dependent individuals. The current article summarizes the neurobiological basis of drug craving, and the pharmacological targets that have been shown to be involved in modulating such craving. The potential usefulness of agents that suppress craving is discussed.


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