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Thursday, July 31, 2008

Patterns of Alcohol Consumption and the Metabolic Syndrome
Journal of Clinical Endocrinology & Metabolism Online July 15, 2008


Protective and detrimental associations have been reported between alcohol consumption and the Metabolic Syndrome. This may be due to variations in drinking patterns and different alcohol effects on the Metabolic Syndrome components.

This study is designed to examine the relationship between alcohol consumption patterns and the Metabolic Syndrome.

In multinomial logistic regression models controlling for demographics, family history of cardiovascular disease and diabetes, and lifestyle factors, increased risk of the Metabolic Syndrome was associated with daily consumption that exceeded U.S. Dietary Guideline recommendations (>1 drink per drinking day for women and >2 drinks per drinking day for men (odds ratio (OR) = 1.60, 95% confidence interval (CI) = 1.22- 2.11)) and binge drinking ≥ once /week (OR (95% CI)=1.51 (1.01-2.29).

By individual metabolic abnormality, drinking in excess of the Dietary Guidelines was associated with an increased risk of impaired fasting glucose/diabetes mellitus, hypertriglyceridemia, abdominal obesity, and HBP.

Public health messages should emphasize the potential cardiometabolic risk associated with drinking in excess of national guidelines and binge drinking.

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